Last year I worked on a flick called Zero Charisma that had a wide shot of 5 talkers around a table playing D&D and while the shot was pretty scripted, the pace was speedy. Boom was impossible, so I engaged automix on all actors, had a Sanken not set to auto dangling in an overhead light for ambience to mask the automix gating and went for it. The end result was really solid. I still had isos in case it didn't work out.